Figure 8
Honokiol protects cardiomyocytes against Dox-induced apoptosis in vivo. (A) Representative TUNEL images, High magnificent images of TUNEL positive cardiomyocytes were presented in the lower left. (Scale bar, 50 µm). (B) Quantitative analysis of myocardial apoptosis. The apoptotic nuclei were stained as brown. (C) Western blots of Caspase 3, cleaved caspase 3 and actin. (D) Protein levels of caspase 3 relative to actin in heart tissue homogenate. (E) Protein levels of cleaved caspase 3 relative to actin. (n = 3–5). **p < 0.01 vs. Control group; #p < 0.05 vs. Dox group. Values are expressed as mean ± SEM.
