Table 3 Bioassay results with diflubenzuron in genome-modified Drosophila.

From: Striking diflubenzuron resistance in Culex pipiens, the prime vector of West Nile Virus

Strain

LC50 in ppm (95% CL)

Resistance Ratio (95% CL)

nos.Cas9

0.34 (0.31–0.37)

1

Dif4 (I1056L)

7.52 (6.73–8.19)

22.1 (19.7–24.5)

Px39 (I1056M)

>1,000

>2,941

  1. LC50 values (in ppm, mg/L) for diflubenzuron are shown for the control flies (nos.Cas9) and the genome modified flies Dif4 (I1056L) and Px39 (I1056M) with the respective 95% confidence limits. The resistance ratio is calculated over the control flies.
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