Figure 7 | Scientific Reports

Figure 7

From: Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins

Figure 7

Effects of pulmonary inflammation + hypoxia exposure and I-BET151 administration on the hypertrophic capacities of soleus muscle subjected to an overload surgery. Hypertrophic capacity was determined by the ratio between soleus weight normalized with tibia length and the mean of the control group. (n = 7–8; Mean ± SEM); NCv: Normoxia control + vehicle; NCiB: Normoxia control + IBET; NSv: Normoxia + Surgery + vehicle; NSiB: Normoxia + Surgery + IBET; HSIv: Hypoxia + Surgery + Inflammation + vehicle; HSIiB: Hypoxia + Surgery + Inflammation + IBET. *Different vs. NCv, NCiB and HSIv, p < 0.05.

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