Figure 5

Dependence of energy (А,C,E,G) and line tension (B,D,F,H) of the pore on its radius r obtained based on the continuum theory of elasticity for model lipid bilayers. Blue curves in all plots correspond to the reference model lipid (B m = 8 k B T, K A m = 100 mN/m, h m = 2 nm, J 0 = 0). (A,B) Spontaneous curvatures J m = +0.1 nm–1 (magenta curves) and J m = –0.1 nm–1 (green curves); (C,D) splay moduli B m = 5.3 k B T (magenta curves) and B m = 12 k B T (green curves); (E,F) lateral stretch/compression moduli K A = 67 mN/m (magenta curves) and K A = 150 mN/m (green curves); (G,H) thicknesses of the hydrophobic part of monolayer h m = 3 nm (magenta curves) and h m = 1.3 nm (green curves). All parameters except indicated are taken the same as of the reference model lipid. Dashed horizontal lines on the panels B,D,F,H correspond to asymptotic values of line tension γ 0 at large (infinite) pore radius.