Table 2 Candidate Genes from Microarray.
From: A Whole Blood Molecular Signature for Acute Myocardial Infarction
Gene | Â | Coefficient | Discovery | Validation | ||||
|---|---|---|---|---|---|---|---|---|
Fold-Change | p-value | adjusted p-value | Fold-Change | p-value | adjusted p-value | |||
HBEGF | heparin-binding EGF-like growth factor | 0.1132 | 5.40 | 7.40E–10 | <0.0005 | 5.16 | 1.6E–06 | <0.0005 |
SYTL3 | synaptotagmin–like 3 | 0.0991 | 3.74 | 7.59E–08 | <0.0005 | 2.17 | 1.1E–02 | 0.088 |
EDN1 | endothelin 1 | 0.0896 | 3.18 | 1.24E–07 | <0.0005 | 1.47 | 1.1E–01 | 0.295 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0583 | 5.80 | 4.24E–08 | <0.0005 | 11.57 | 2.2E–12 | <0.0005 |
NFKBIA | NF–Kappa–B inhibitor alpha | 0.0563 | 3.55 | 2.05E–07 | <0.0005 | 5.41 | 1.4E–10 | <0.0005 |
VPS8 | vacuolar protein sorting 8 homolog | 0.0555 | 3.08 | 3.14E–07 | <0.005 | 1.80 | 2.9E–02 | 0.140 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0461 | 8.39 | 3.36E–08 | <0.0005 | 6.04 | 1.2E–07 | <0.0005 |
SULF1 | sulfatase 1 | 0.0283 | 8.89 | 1.97E–06 | <0.005 | 2.74 | 1.9E–03 | <0.05 |
RNASE1 | ribonuclease, RNase A family, 1 | 0.0119 | 4.45 | 3.29E–06 | <0.005 | 2.08 | 6.9E–05 | <0.05 |
CCL20 | chemokine (C–C motif) ligand 20 | 0.0014 | 6.23 | 3.65E–06 | <0.005 | 8.45 | 1.8E–10 | <0.0005 |
MGP | matrix Gla protein | 0.0013 | 7.86 | 5.16E–06 | <0.005 | 5.83 | 9.6E–09 | <0.0005 |
