Figure 2

Crystal structure of C-terminal catalytic domain of UGGT. (a) Crystal structure of CAT domain in complex with UDP-Glc is shown as ribbon models. The bound UDP-Glc and Ca²⁺ are shown as stick and sphere models, respectively. The catalytic active site of UGGT in the UDP-Glc or UDP-bound form is shown in (b) and (c), respectively. Residues involved in binding to Ca²⁺ and UDP-Glc or UDP are numbered and shown in the stick model. The UDP-Glc and UDP molecules are coloured yellow and cyan.