Figure 4
From: Dual “mAb” HER family blockade in head and neck cancer human cell lines combined with photon therapy
Cell invasion under each treatment condition, graphically represented by the mean invasion curves +/− standard deviation. Blue curve, control; black curve, pertuzumab 20 μg/mL; red curve, cetuximab 5 nM; green curve, cetuximab 5 nM + pertuzumab 20 μg/mL. Cell invasion was measured by an IncuCyte Zoom scratch wound analyser for each cell line under the following treatment conditions: control; cetuximab 5 nM; pertuzumab 20 μg/mL; cetuximab 5 nM + pertuzumab 20 μg/mL; 10 Gy; 10 Gy + cetuximab 5 nM; 10 Gy + pertuzumab 20 μg/mL; 10 Gy + cetuximab 5 nM + pertuzumab 20 μg/mL. Reduced Matrigel (dilution 1/10) was set into each wound. Each experiment was performed in triplicate.
