Figure 1

Titanium quantification in brains of young adult rats (A) and aging rats (B) of exposed and control animals by inductively coupled plasma mass spectrometry (ICP-MS) at 3 days and 28 days after the end of the inhalation exposure. Results represents the median of n = 5 to 8 animals. Statistical comparison between treated and control groups was by two way ANOVA after Box-Cox transformation on Ti concentration variable and Bonferroni post hoc test.