Figure 6

IL-1β expression (red fluorescence) in the midbrain of (A) 12–13 wk control, (B) 12–13 wk nano-aerosol-exposed; (C) 19 mo control; and (D) 19 mo nano-aerosol-exposed rats at 28 days after the end of exposure. A minimum of 3 locations on each section (2 sections per slide), 3 slides and n = 3 per group were analyzed. Relative fluorescence per unit area is represented in graph shown. *p < 0.050 compared to 12–13 wk control; †p < 0.050 compared to 19 mo control. Scale bar = 1000 µm.