Figure 2
From: Host genetic background influences diverse neurological responses to viral infection in mice
The varied responses to TMEV infection for mice from different CC strains and sexes are reflected by the percentage of weight lost/gained. (a) Shows weight changes in the different strains over the course of the experiment, while (b) shows percent weight changes based on the starting (day 0) weights of the mice. Group B percent weight change at 5 dpi, in relation to TMEV RQ levels, was used to evaluate differences in response to TMEV: in (c), the left y-axis displays the percent weight change at 5 dpi, relative to baseline (pre-infection); the right y-axis shows TMEV RQ levels at 7 dpi. Box plots show data quartiles and median; whiskers represent extreme data outcomes. Dots show corresponding levels of TMEV transcript (RQ values). A higher infection level (shown here as TMEV expression RQ) did not correlate with greater % weight change for CC041, which also showed gender-specific responses.
