Figure 2 | Scientific Reports

Figure 2

From: TNF-α mRNA is negatively regulated by microRNA-181a-5p in maturation of dendritic cells induced by high mobility group box-1 protein

Figure 2

Validation of the microarray expression patterns of miR-181a-5p in DCs stimulated by HMGB1. Immature DCs were cultured with the indicated doses of HMGB1 (100 and 1000 ng/ml) or without HMGB1 (0 ng/ml, control). The up-regulation of miR-181a-5p in DCs stimulated by HMGB1 (100 and 1000 ng/ml) was significant compared with the DCs cultured without HMGB1 (0 ng/ml, as control). Results of 3 independent experiments were shown as the mean ± SEM. **P < 0.01 vs. 0 ng/ml group.

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