Table 1 Distribution of age, sex, glycosylation features and metabolic parameters within the Leiden Longevity study population.
From: Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health
| Â | mean | SD | range | N |
|---|---|---|---|---|
Age (years) | 59.1 | +/−6.7 | 30.2–79.2 | 1826 |
Sex | 47.1% male | — | — | 1826 |
CRP (mg/L) | 2.86 | +/−9.5 | 0.2–228.7 | 1813 |
IL-6 (pg/mL) | 0.67 | +/−1.2 | 0–19.6 | 1705 |
Glucose (mmol/L) | 5.94 | +/−1.5 | 2.5–26.3 | 1816 |
Insulin (mU/L) | 23.23 | +/−22.1 | 2–238 | 1766 |
TC (mmol/L) | 5.55 | +/−1.2 | 1.4–10.8 | 1820 |
LDLC (mmol/L) | 3.33 | +/−1.0 | 0.7–7.9 | 1772 |
HDLC (mmol/L) | 1.42 | +/−0.4 | 0.2–3.2 | 1819 |
TG (mmol/L) | 1.82 | +/−1.2 | 0.2–21.2 | 1820 |
free T3 (pmol/L) | 4.12 | +/−0.8 | 1.8–14.3 | 1819 |
smoking | 13.6% smoking | — | — | 1587 |
CMV serostatus | 45.9% positive | — | — | 1437 |
longevity | 64.1% offspring | — | — | 1826 |
IgG1 fucosylation | 91.2% | +/−4.1 | 69.3–99.5 | 1825 |
IgG2 fucosylation | 97.4% | +/−0.9 | 92.6–99.1 | 1826 |
IgG1 bisection | 19.1% | +/−3.3 | 6.5–35.8 | 1825 |
IgG2 bisection | 13.9% | +/−2.7 | 6.4–26.5 | 1826 |
IgG4 bisection | 19.6% | +/−4.4 | 8.8–41.3 | 1742 |
IgG1 galactosylation | 50.1% | +/−6.4 | 24.6–70.8 | 1825 |
IgG2 galactosylation | 39.5% | +/−6.2 | 9.0–61.3 | 1826 |
IgG4 galactosylation | 43.7% | +/−6.9 | 14.5–66.0 | 1742 |
IgG1 sialylation | 6.8% | +/−1.4 | 2.5–14.0 | 1825 |
IgG2 sialylation | 6.2% | +/−1.4 | 1.4–11.9 | 1826 |
IgG4 sialylation | 9.1% | +/−2.0 | 3.2–18.9 | 1742 |
IgG1 sialic acid per gal | 13.6% | +/−1.6 | 9.0–21.5 | 1825 |
IgG2 sialic acid per gal | 15.5% | +/−1.7 | 9.4–22.5 | 1826 |
IgG4 sialic acid per gal | 20.7% | +/−2.0 | 13.8–30.8 | 1742 |
