Table 1 Characteristics of study subjects at baseline.

From: Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study

 

Control (n = 34)

Probiotic (n = 34)

Sex (male/female)

20/14

29/5

Age (years)

65.0 ± 8.3

64.0 ± 9.2

BMI (kg/m2)

24.6 ± 2.6

24.2 ± 2.6

Duration of diabetes (years)

12.2 ± 7.2

13.9 ± 9.6

HbA1c (%)

6.8 ± 0.5

6.9 ± 0.5

Glycoalbumin (%)

17.6 ± 3.4

17.6 ± 2.3

Fasting blood glucose (mg/dL)

129.5 ± 26.6

128.5 ± 19.1

Fasting C-peptide (ng/ml)

1.8 ± 0.7

1.7 ± 0.6

T-CHO (mg/dL)

182.9 ± 28.2

188.2 ± 31.7

HDL-C (mg/dL)

55.7 ± 14.7

54.0 ± 15.2

TG (mg/dL)

109.4 ± 45.0

104.7 ± 35.6

hs-CRP (mg/dL)

403.5 (166.0–757.0)

370.5 (218.0–610.0)

TNF-α (pg/mL)

0.9 ± 0.3

1.1 ± 0.5

IL-6 (pg/mL)

1.8 ± 0.9

1.7 ± 1.2

Adiponectin (μg/mL)

8.3 ± 2.9

10.3 ± 7.2

LBP (μg/mL)

11.2 ± 3.9

10.0 ± 2.2

Medication for diabetes

 No medication

8

6

 Insulin only or with oral therapy

4

3

 Oral therapy only

  SU

7

9

  Metformin

16

17

  Thiazolidine

1

5

  DPP-4 inhibitor

16

22

  Glinide

6

3

  SGLT2 inhibitor

1

2

  GLP-1-receptor agonist

1

0

  1. Data are mean ± SD or median (interquartile range; 25–75%). BMI, Body mass index; T-CHO, total cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides; hs-CRP, high-sensitivity C-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; LBP, lipopolysaccharide binding protein; SU, sulfonylurea; DPP-4 inhibitor, dipeptidyl peptidase-4 inhibitor; SGLT2 inhibitor, sodium-dependent glucose cotransporter-2 inhibitor; GLP-1-receptor agonist, glucagon-like peptide-1-receptor agonist.