Figure 7 | Scientific Reports

Figure 7

From: Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model

Figure 7

SPECT/CT study. (a) Representative SPECT/CT images. 111In-labelled anti-TF 1849 IgG (left) more efficiently accumulated in the intracranial tumours overexpressing TF compared with 111In-labelled control IgG (right). (b) Quantitative analysis of the SPECT/CT study revealed significant differences in the mean (upper) and maximum (lower) values of tumour uptake between the 111In-labelled anti-TF 1849 IgG-administered and control IgG-administered groups (P < 0.01). N = 4 mice per group. The data are shown as the means ± SD. Points, mean; bars, SD.

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