Figure 5
Analysis of relative hair color gene expression for evidence of a transcriptome profile, gp100 expression and MC4R protein expression in the skin of Cdk5 knockdown mice. (A) Western blot analysis of MITF, TYRP1, TYRP2, PAX3, MC1R, gp100 and MC4R protein expression in the skin of Cdk5 knockdown mice comp ompared to the wild-type mouse ared with wild-type mice. (B) The abundance of the MITF, TYRP1, TYRP2, PAX3 and MC1R proteins was quantified using Image-Pro Plus software and normalized relative to the abundance of β-actin. Bars represent the mean ± standard error (n = 3). ***P < 0.001.
