Figure 4 | Scientific Reports

Figure 4

From: Cytokine-induced autophagy promotes long-term VCAM-1 but not ICAM-1 expression by degrading late-phase IκBα

Figure 4

3-MA inhibits cytokines-induced VCAM-1 transcripts at 6 h but not at 2 h. (A,B) HUVECs were pretreated with 5 mmol/L 3-MA, 100 nmol/L Bafilomycin A (BAF) or 10 μmol/L SB202190 (SB) for 30 min followed by 10 ng/mL IL-1β or 10 ng/mL TNFα for 2 h (A) or 6 h (B). VCAM-1 and ICAM-1 mRNAs were quantified by qPCR using peptidylprolyl isomerase A (PPIA) as reference. Each bar denotes mean ± SD of two independent experiments.

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