Figure 1
From: Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein
Cholesterol efflux capacity of human (h) EL-serum, hEL-apoB-DS and hEL-HDL. (a) Total CEC was measured in J774 macrophages following induction of ABCA1 expression. (b) ABCA1-independent efflux was measured without ABCA1 upregulation and (c) ABCA1-dependent CEC was obtained by subtraction of the ABCA1-independent efflux from the total efflux. The cholesterol efflux was expressed as the radioactivity in the medium relative to total radioactivity in the medium and cells. Results are mean ± SEM of 5 independent modifications of pool-serum, each measured in duplicates and analysed by two-tailed unpaired t-test. *P < 0.05, **P < 0.01, ***P < 0.001.
