Figure 5
From: Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein
EL overexpression in mice decreases HDL and apoA-I content as well as CEC of serum (a) Sudan black staining following non-denaturing 4–16% gel electrophoresis and (b) Western blot (apoA-I) following SDS-PAGE of serum and apoB-DS. Full images with 5 lanes per sample are shown in Supplementary Fig. S5a,b. (c) Total CEC measured in J774 macrophages following induction of ABCA1 expression. Results are mean ± SEM of 2 independent in vivo modifications, with 12 EL-Ad and 4 EV-Ad -transduced mice per each modification, measured twice in duplicates and analysed by two-tailed unpaired t-test. ***P < 0.001.
