Figure 1 | Scientific Reports

Figure 1

From: Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis

Figure 1

YC-1 inhibited growth in the gastric cancer cell line 58As9. (a) Viability of YC-1-treated 58As9 cells under normoxia and hypoxia; viability of HIF-1α KD (KD) cells was evaluated in parallel. (b) Cell death rate in 58As9 cells with or without YC-1 (10 μM) under normoxia and hypoxia. (c) Western blot analysis of HIF-1α expression in 58As9 cells under normoxia and hypoxia with or without YC-1 (10 μM) treatment for 8 and 12 h. β-actin was equally expressed in all cells. ns: not significant, **p < 0.01.

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