Figure 6 | Scientific Reports

Figure 6

From: Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability

Figure 6

Deletion of nmMLCK abrogated IH-induced endothelial dysfunction. Effect of IH exposure on concentration-response curves to acetylcholine (Ach) in aortic rings with intact endothelium pre-contracted with the thromboxane A2 analogue from (A) wild-type and (B) nmMLCK deficient mice (n = 12). **P < 0.01, ***P < 0.001.

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