Table 1 Comparison of various sensors for cortisol with respect to substrates, buffer media, linear range and detection limit.

From: Portable biosensor for monitoring cortisol in low-volume perspired human sweat

Substrate

Detection method

Buffer media

Dynamic range

Detection limit

Ref.

Au nanowire

Square wave voltammetry

PBS

3.7–12 µg/mL

3.7 µg/mL

43

Immune-chromatographic strip

Immuno-chromatography

PBS

1–10 ng/mL

1 ng/mL

44

Disposable disc-chip (acrylic resin)

Immuno-chromatography

Saliva

0.4–11.3 ng/mL

0.4 ng/mL

45

SAM modified microfabricated interdigitated Au electrodes

Cyclic voltammetry

PBS

3.6 pg/mL –36 ng/mL

3.6 pg/mL

46

Zinc oxide on flexible nanoporous membrane

Electrochemical Impedance Spectroscopy

Human sweat

10–200 ng/mL

1 ng/mL

30

MoS2 Nanosheet on flexible nanoporous membrane

Electrochemical Impedance Spectroscopy

Human sweat

1–500 ng/mL

1 ng/mL

This work

  1. Physiological relevant range reported for cortisol in human sweat is 8–140 ng/mL10.