Table 1 Effects of ghrelin on glucose and insulin levels after 2 weeks of administration.

From: Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington’s disease

 

WT vh

R6/2 vh

R6/2 ghrelin

p-value#

p-value§

Glucose metabolism

Basal glucose (mmol/L)

7.85 ± 0.55

18.21 ± 1.99

17.88 ± 2.03

0.002

>0.9999

Basal Insulin (μg/L)

1.18 ± 0.23

0.40 ± 0.08

0.43 ± 0.07

0.038

>0.9999

HOMA-IR

11.17 ± 2.43

8.68 ± 2.04

7.72 ± 1.47

>0,9999

>0,9999

HOMA-β

147.3 ± 28.41

13.66 ± 2.86

19.47 ± 5.99

<0,0001

>0,9999

  1. The table shows the effects of ghrelin after 2 weeks of treatment. Data are expressed as mean ± SEM. Two-way ANOVA with Bonferroni post hoc test for multiple comparisons was used to analyse data. #Represents the p-value between WT and R6/2 treated with vehicle, and §represents the p-value between vehicle and ghrelin treatment in R6/2 mice. A p-value below 0.05 was considered significant.
Back to article page