Figure 1

Production of crosslinked nanobubbles (CL-NBs). (A) UV irradiation is used to form a crosslinked network of the biodegradable polymer N,N-diethyl acrylamide (NNDEA) with cross-linker N,N-bis(acryoyl) cystamine (BAC). (B) Schematic diagram of a CL-NB. A P(NNDEA-co-BAC) crosslinked mesh stabilizes an outer pluronic/phospholipid layer enclosing a perfluorocarbon gas core. Illustration credit to Tiffany Yang.