Table 2 KEGG pathway enrichment analysis of hypoxia-regulated genes.

From: Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax – a liver transcriptomics approach

Spalax

rat

upregulated

downregulated

upregulated

downregulated

circadian rhythm

metabolic pathways

metabolic pathways

metabolic pathways

MAPK signaling pathway

metabolism of xenobiotics by cytochrome P450

RNA transport

RIG-I-like receptor signaling pathway

adipocytokine signaling pathway

drug metabolism - cytochrome P450

glycolysis/gluconeogenesis

terpenoid backbone biosynthesis

insulin signaling pathway

glutathione metabolism

ribosome biogenesis in eukaryotes

cytosolic DNA-sensing pathway

pathways in cancer

histidine metabolism

pentose phosphate pathway

Hepatitis C

  1. Shown are the ‘Top Five’ KEGG pathways significantly enriched (p < 0.01) with significantly regulated genes (p < 0.01) in the two species, respectively.
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