Figure 4 | Scientific Reports

Figure 4

From: Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Figure 4

Regulation of autophagy-lysosome system. (A) Transcript level of Atg5, Ulk1, LC3b, Bnip3, cathepsin B and cathepsin L in Sham mice, vehicle-MCAO mice (MCAO) and PINTA745-MCAO mice (MCAO + PINTA) 15 days after middle cerebral artery occlusion (MCAO). Representative immunoblots (upper panel) and quantification (lower panel) of Atg5-Atg12 (B), Atg13 (C) and p62 (D) protein content in quadriceps muscle of Sham, MCAO and MCAO + PINTA mice. Data are means ± SEM (n = 6–9/group). **P < 0.01.

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