Figure 1 | Scientific Reports

Figure 1

From: Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes

Figure 1

Timing of father to son transmission of HSV and viral isolate acquisition. HSV-1 isolate R-13 was acquired during an orolabial recurrence from a father with lifelong chronic infection, characterized by oral lesion recurrences 6–8 times per year. The father acquired his primary infection at age 3, more than four decades prior. At age 27, the father is inferred to have transmitted HSV-1 to his 2-year old son, who experienced gingivostomatitis with high fever. After resolution of the primary infection, the son likewise experienced recurrent orolabial lesions at a frequency of 6–8 episodes/year. Isolate N-7 was acquired during an orolabial recurrence from the son 17 years after his primary infection. The isolates were obtained on separate occasions, two years apart.

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