Figure 2

Schematic illustration of the miR-16 family and miR-103/miR-107 binding sites in the 3′UTR of the HTR4b/i isoforms. Binding sites (I-III) are based on predictions by TargetScan, miRanda and/or RegRNA. The position of HTR4b/i c.*61 T > C is highlighted in red within the seed region (nucleotides 2–8) of the indicated miRNA binding site.