Table 1 HTR4b c.*61 T > C (rs201253747) genotypes in IBS patients and healthy controls

From: miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome

Genotype

c.*61 T/c.*61 T

c.*61 T/ c.*61 C

c.*61 C/c.*61 C

MAF (C)

P-value/OR/95% CI

IBS-D

825

7

0

0.00420

 

IBS-C

612

2

0

0.00163

 

controls

2266

7

0

0.00154

0.049/2.74/0.961-7.854 (IBS-D vs. controls)

non-IBS-D

2878

9

0

0.00156

0.039/2.71/1.007-7.308 (IBS-D vs. non-IBS-D)

  1. IBS, Irritable bowel syndrome; D, diarrhoea; C, constipation; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval.
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