Figure 5
From: Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents
Lactobacillus paracasei Modulates Host Amino Acid, Biogenic Amine & Phosphotidylcholine Metabolism Independently of GLP-1-Expression. (A) Experiment II: Serum metabolome heatmap, with dendogram clustering according to sample likeness. (B) Principle Coordinate Analysis (PCoA) plot displays HFC (green), PNZ (.blue) and GLP1 (red) samples. (C,D) Quantitative data is displayed for the metabolites which were significantly altered by GLP1 or PNZ; this includes amino acids and biogenic amines, as well as diacyl-phosphatidylcholine (PC aa) and acyl-alkyl-phosphatidylcholine (PC ae). *(q < 0.05), **(q < 0.01), ***(q < 0.001), ****(q < 0.0001) represent significant differences between both PNZ/GLP1 and HFC. Plots depict individual replicates (n = 10) with mean and SEM.
