Figure 2 | Scientific Reports

Figure 2

From: Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence

Figure 2

H. pylori gGT activity induces a strong innate immune response. C57Bl/6 mice were infected for one month. (a) Haematoxylin-eosin (HE) and chloroacetate esterase (CAE) staining of murine stomach sections. Images from representative mice of each group are shown. Number of CAE+ cells per high power field (HPF) was determined. Data are derived from three independent experiments. (b) mRNA expression levels of chemokines (LIX, MIP-2) and cytokines (TNFα, IL-1β) associated with the innate immune response determined by quantitative PCR. Results from four to six independent experiments are included. Kruskal-Wallis test followed by Dunn’s test for multiple comparisons. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. Horizontal bars indicate medians.

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