Table 1 Differential gene expression by PSA-lacking and -carrying NCAM fragments. The table shows the relative increase of Nr2f6, Lrp2 and Snca mRNA levels in cerebellar neurons after different treatments performed in microarray 1 or 2 (+apro, aprotinin; chNCAM-Ab, chicken NCAM antibody; rbNCAM-Ab, rabbit NCAM antibody; rbL1-Ab, rabbit L1 antibody; rL1-Ab, rat L1 antibody; rbCHL1-Ab, rabbit CHL1 antibody; rbIg, non-immune rabbit control antibody; rIg, non-immune rat control antibody; EndoN/chNCAM-Ab, chicken NCAM antibody after EndoN pretreatment).
microarray | treatment | Nr2f6 | Lrp2 | Snca |
|---|---|---|---|---|
1 | chNCAM-Ab vs untreated | 1.320 ± 0.023 | 1.415 ± 0.021 | 1.251 ± 0.010 |
1 | chNCAM-Ab vs EndoN/chNCAM-Ab | 1.349 ± 0.025 | — | — |
1 | EndoN/chNCAM-Ab vs untreated | — | 1.267 ± 0.011 | 1.249 ± 0.021 |
2 | rbNCAM-Ab vs rbCHL1-Ab | 1.425 ± 0.183 | 1.965 ± 0.247 | 1.275 ± 0.025 |
2 | rbNCAM-Ab vs rbL1-Ab | 1.595 ± 0.098 | 1.524 ± 0.215 | 1.505 ± 0.132 |
2 | rbNCAM-Ab vs rIg | 2.205 ± 0.256 | 1.313 ± 0.379 | 1.284 ± 0.022 |
2 | rbNCAM-Ab vs rL1-Ab | 1.915 ± 0.154 | 1.639 ± 0.060 | 1.228 ± 0.098 |
2 | rbNCAM-Ab vs rL1-Ab + apro | 2.112 ± 0.366 | 1.496 ± 0.179 | 1.248 ± 0.071 |
2 | rbNCAM-Ab vs rbNCAM-Ab + apro | 0.908 ± 0.079 | 1.800 ± 0.039 | 1.246 ± 0.070 |
