Figure 4 | Scientific Reports

Figure 4

From: Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test

Figure 4

Female Creb1DBHCre/Crem−/− (left panel) and Creb1TPH2Cre/Crem−/− (right panel) mice do not show gross abnormalities and altered behavior under basal conditions. (a,b) body weight gain, (c,d) spontaneous locomotor activity assessed by open field test (OFT), (e, f) motor coordination assessed by rotarod test (ROT), (g,h) depressive-like behavior assessed by tail suspension test (TST). Data are the mean ± SEM, n = 5–12.

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