Figure 2 | Scientific Reports

Figure 2

From: HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication

Figure 2

The dynamic communities of the HtrA1 trimeric protein are shown in different colors. (a) Intra-monomer community in the active trimer. L3 loop residues (Arg302-Arg310) of monomer B and LD residues (284–290) from monomer A belong to the same dynamic community. (b) Active trimer form. (c) Inactive trimer form. (d) Mutant R302A trimer form. Black regions in (b) and (d) indicate L3 loop independent communities.

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