Figure 2
From: A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
Effect of chloroquine on nanoparticle uptake in macrophages. (a) Viability of Raw 264.7, J774A.1, and Kupffer cells in response to chloroquine and nanoparticles. The left side of the dashed line indicates drug concentrations used in the nanoparticle uptake study. (b) Suppression of nanoparticle uptake upon exposure to chloroquine in Raw 264.7, J774A.1, and Kupffer cells. Values are normalized to those of control cells. Data is presented as mean ± s.d. of triplicates. Statistics by Student’s t-test. *P < 0.05; **P < 0.01; ***P < 0.001, compared with cells exposed to nanoparticles.
