Figure 2 | Scientific Reports

Figure 2

From: Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model

Figure 2

Treated mice developed neutralizing antibodies that delayed β-cell loss. (A) Blood samples were collected by submandibular bleeding. α-hIAPP antibody serum titer was evaluated by ELISA assay (N = 13, sera dilution 1:500, values are means ± s.d., Student’s t-test **P < 0.005). Grey bars denotes the mock treatment and the black bar denotes the hIAPP treated group. (B) At the experiment endpoint, three mice from each group were chosen randomly. The pancreas was removed and total insulin content per tissue weight was determined (data point values are presented).

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