Figure 4

Antibodies derived from immunized mice recognize and neutralize hIAPP oligomers. Rin-m cells were treated with hIAPP oligomers with or without antibodies derived from the immunized (red) or the mock group (blue) at various concentrations. Cell viability was determined by the MTT reduction assay and treated and non-treated cells were compared (values are means ± s.d., Student’s t-test **P < 0.005).