Figure 2 | Scientific Reports

Figure 2

From: Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model

Figure 2

Correlation of Optical Imaging with Cell Concentration within Engineered TNBC Surrogates. (a,c) Fluorescence (GFP) & bioluminescence imaging (BLI) of increasing cell concentrations (TNBC model) on day 0. (b,d) Graphical representation of region of interest measurements (ROI) from GFP and BLI completed on the day of surrogate setup (day 0). R2 value obtained from correlation analysis of cell concentration seeded and imaging signal shows a strong correlation for both imaging methods (GFP: R2 = 0.974 (p = 0.013), BLI: R2 = 0.939 (p = 0.031), Pearson correlation coefficient). n = 3–6 replicate surrogates per cell concentration. Data in b & d represent mean ± SE.

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