Figure 4
From: Asymmetric Sensory-Motor Regeneration of Transected Peripheral Nerves Using Molecular Guidance Cues

Regenerated split fascicles are electrically conductive. (A) Setup for measuring Compound Nerve Action Potential (CNAP). Bipolar hook electrodes provided stimulus pulses and the response recorded distally from the Y-split regenerated nerve fascicles. (B) Representative STA-CNAP waveform showing the stimulus artifact followed by fast, medium, and slow peak-responses. (C) Individual CNAP peaks with Conduction Velocity evoked by each treatment. The dotted lines indicate slow, medium, and fast responses from conducting fibers. (D) Corresponding individual area under the curve (AUC). Black bars represent the median evoked response per treatment. (N = 3–6 animals/group; data represents evoked CNAPs).