Table 1 Characteristics of the included studies on SNP rs2075876 (G > A) and rs760426 (A > G) (SNP = single nucleotide polymorphism; NA = not available; HB = hospital based).
Year | Country | Ethnicity | Diagnostic criteria | Genotyping | Mean age | Female % | Control source | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
case | control | case | control | |||||||||
SNP rs2075876(G > A) | Terao C | A | 2011 | Japan | Asian | American College of Rheumatology for RA (1987) | microarrays | 63.0 ± 12.5 | 52.0 ± 15.8 | 82.1 | 60.6 | HB |
B | 2011 | microarrays | 60.8 ± 11.5 | 38.1 ± 11.9 | 84.1 | 39.6 | HB | |||||
C | 2011 | microarrays | 61.4 ± 11.5 | 52.5 ± 15.2 | 81.4 | 44.4 | HB | |||||
García-Lozano JR | 2013 | Spain | Caucasian | American College of Rheumatology for RA (1987) | Taqman SNP genotyping assay | 49.2 ± 14.8 | NA | 74.3 | NA | HB | ||
Shao S | 2014 | China | Asian | American College of Rheumatology for RA (1987) | SNaPshot assay | 48.7 ± 14.2 | 47.0 ± 16.3 | 80.6 | 37.0 | HB | ||
Feng ZJ | 2015 | China (Han) | Asian | American College of Rheumatology for RA (1987) | Taqman SNP genotyping assay | 54.1 ± 11.2 | 52.4 ± 11.8 | 53.5 | 58.5 | HB | ||
Li X | 2016 | China (Shaanxi) | Asian | American College of Rheumatology for RA (1987) | Snapshot Assay | 43.5 ± 19.2 | 44.3 ± 17.8 | 64.3 | 59.7 | HB | ||
SNP rs760426 (A > G) | Terao C | A | 2011 | Japan | Asian | American College of Rheumatology for RA (1987) | microarrays | 63.0 ± 12.5 | 52.0 ± 15.8 | 82.1 | 60.6 | HB |
B | 2011 | microarrays | 60.8 ± 11.5 | 38.1 ± 11.9 | 84.1 | 39.6 | HB | |||||
C | 2011 | microarrays | 61.4 ± 11.5 | 52.5 ± 15.2 | 81.4 | 44.4 | HB | |||||
Shao S | 2014 | China | Asian | American College of Rheumatology for RA (1987) | SNaPshot assay | 48.7 ± 14.2 | 47.0 ± 16.3 | 80.6 | 37.0 | HB | ||
Feng ZJ | 2015 | China (Han) | Asian | American College of Rheumatology for RA (1987) | Taqman SNP genotyping assay | 54.1 ± 11.2 | 52.4 ± 11.8 | 53.5 | 58.5 | HB | ||
Li X | 2016 | China (Shaanxi) | Asian | American College of Rheumatology for RA (1987) | Snapshot Assay | 43.5 ± 19.2 | 44.3 ± 17.8 | 64.3 | 59.7 | HB | ||
