Table 2 Clinicopathologic features of patients with and without lymph node metastasis.

From: Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis

Variable

Lymph node metastasis

P value

Negative

Positive

(n = 97)

(n = 18)

Age mean (range)

56 (41–76)

58 (31–85)

0.474

Menopause

53 (54.6%)

11 (61.1%)

0.797

Histologic type

  

0.909

  Endometrioid Grade 1

66 (68.0%)

12 (66.7%)

 

  Endometrioid Grade 2

15 (15.5%)

2 (11.1%)

 

  Endometrioid Grade 3

7 (7.2%)

2 (11.1%)

 

  Nonendometrioid

9 (9.3%)

2 (11.1%)

 

Tumor sizea

  

0.237

  ≤ 2 cm

24 (24.7%)

2 (11.1%)

 

  > 2 cm

73 (75.3%)

16 (88.9%)

 

  Myometrial invasionb

  

0.012

  ≤ 1/2

70 (72.2%)

7 (38.9%)

 

  > 1/2

27 (27.8%)

11 (61.1%)

 

Cervical stromal invasion

  

0.332

  Present

5 (5.2%)

2 (11.1%)

 

  Absent

92 (94.8%)

16 (88.9%)

 

Lymph-vascular invasion

  

< 0.001

  Present

13 (13.4%)

13 (72.2%)

 

  Absent

84 (86.6%)

5 (27.8%)

 

Risk of recurrence

  

< 0.01

  low-intermediate risk

77 (90.6%)

8 (9.4%)

 

  high risk

20 (66.7%)

10 (33.3%)

 
  1. NOTE: aTumor size was classified based on maximum tumor dimension. bDepth of myometrial invasion was divided into two categories: ≤ 1/2 or > 1/2 of width of muscle layer. cStatistical analysis was performed using the Mann–Whitney test and Fisher’s exact tests, where appropriate. Significant correlations are marked in bold.
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