Figure 1

Expression levels of neuronal markers in iN cells at day 14 after the transfection of human BAM factors. Beta III tubulin (neuronal marker) positive iN cells derived from healthy control (A) and NF1 patient (B). (C) NF1 mRNA expression levels were quantified by real-time PCR. Two-way ANOVA/Sidak’s test, n = 6 each group. (D–F) MAP2 (pan-neuronal marker), RBFOX3 (mature neuronal marker), and S100A4 (fibroblast marker) mRNA expression level, respectively. Two-way ANOVA/Tukey’s test, n = 6 each group. Open circles show healthy controls and filled circles show NF1 patients.