Table 5 Comparison of target and OARs’ dose-volume parameters in the subgroup of left-lung and right-lung tumors.

From: Dosimetric comparison of the helical tomotherapy, volumetric-modulated arc therapy and fixed-field intensity-modulated radiotherapy for stage IIB-IIIB non-small cell lung cancer

   

TOMO

VMAT

IMRT

P value

T vs. V

T vs. I

V vs. I

Left

Lung

V20 (%)

17.76 ± 6.94

22.81 ± 6.77

22.98 ± 5.86

0.156

0.028

0.968

V30 (%)

12.23 ± 6.51

15.72 ± 5.02

16.38 ± 4.68

0.208

0.018

0.756

Heart

MHD (Gy)

17.55 ± 10.16

8.80 ± 5.45

14.90 ± 7.42

0.047

0.196

0.065

V10 (%)

48.63 ± 28.40

23.89 ± 14.43

41.31 ± 22.53

0.048

0.197

0.072

V20 (%)

37.05 ± 25.15

15.00 ± 10.11

28.89 ± 18.52

0.038

0.127

0.066

V30 (%)

26.01 ± 18.21

10.81 ± 8.03

19.57 ± 12.81

0.045

0.094

0.097

Right

PTV

CI

0.74 ± 0.06

0.81 ± 0.05

0.75 ± 0.07

0.000

0.787

0.001

HI

0.15 ± 0.04

0.09 ± 0.03

0.11 ± 0.02

0.001

0.003

0.048

Lung

MLD (Gy)

13.56 ± 3.46

12.42 ± 2.83

12.09 ± 3.15

0.188

0.037

0.509

Heart

V5 (%)

47.73 ± 26.84

46.68 ± 28.28

37.08 ± 21.08

0.779

0.013

0.070

V10 (%)

34.93 ± 23.29

34.62 ± 24.97

24.50 ± 16.79

0.718

0.037

0.086

  1. Abbreviation: OAR = organs at risk; PTV = planning target volume; CI = conformity index; HI = heterogeneity index; T = helical tomotherapy; V = volumetric-modulated arc therapy; I = intensity-modulated radiotherapy; MHD = mean heart dose; MLD = mean lung dose.
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