Table 1 Numbers of GWAS samples and SNPs after quality control.

From: Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Phenotype

Case

Control1

Genotyped SNP

Sample

Male

Female

Sample

Male

Female

IONFH

1,547

777

770

59,103

32,135

26,968

525,308

Stratified analysis based on risk factors 2

Steroid-associated

1,058

386

672

59,103

32,135

26,968

525,264

Alcohol-associated

351

316

35

59,103

32,135

26,968

524,775

Neither-associated

132

70

62

59,103

32,135

26,968

523,825

Stratified analysis based on alcohol intake 3

Alcohol-associated

351

316

35

3,647

3,349

298

525,254

  1. 1Derived from BioBank Japan. 2Six patients could not be classified because sufficient information for classification could not be obtained. 3Controls were matched for alcohol-drinking history (400 ml or more ethanol consumption per week). IONFH: idiopathic osteonecrosis of the femoral head.