Table 2 Association of SNPs within 2q32.3 and 6p21.32 on steroid-associated ONFH considering underlying disease
From: Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head
Case | Control | rs13426947 (2q32.3) | rs9268978 (6p21.32) | |||||||
---|---|---|---|---|---|---|---|---|---|---|
RAF | OR | P | RAF | OR | P | |||||
Case | Control | Case | Control | |||||||
Steroid-associated ONFH | 1,058 | 59,103 | 0.338 | 0.278 | 1.33 | 1.63 × 10−9 | 0.112 | 0.081 | 1.52 | 1.16 × 10−8 |
Underlying disease | ||||||||||
SLE | 433 | 59,103 | 0.378 | 0.278 | 1.58 | 9.48 × 10−11 | 0.136 | 0.081 | 1.88 | 1.13 × 10−9 |
Not SLE | 625 | 59,103 | 0.311 | 0.278 | 1.16 | 0.0138 | 0.096 | 0.081 | 1.26 | 0.0219 |