Table 2 Association of SNPs within 2q32.3 and 6p21.32 on steroid-associated ONFH considering underlying disease

From: Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Case

Control

rs13426947 (2q32.3)

rs9268978 (6p21.32)

RAF

OR

P

RAF

OR

P

Case

Control

Case

Control

Steroid-associated ONFH

1,058

59,103

0.338

0.278

1.33

1.63 × 10−9

0.112

0.081

1.52

1.16 × 10−8

Underlying disease

SLE

433

59,103

0.378

0.278

1.58

9.48 × 10−11

0.136

0.081

1.88

1.13 × 10−9

Not SLE

625

59,103

0.311

0.278

1.16

0.0138

0.096

0.081

1.26

0.0219

  1. ONFH: osteonecrosis of the femoral head, RAF: risk allele frequency, OR: odds ratio, SLE: systemic lupus erythematosus.