Table 1 Patient clinicopathological characteristics and relationship with PKM2 expression.

From: Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma

Characteristics

N

Cirrhosis HCC

P value

N

Non-cirrhosis HCC

P value

low

high

low

high

Gender

Female

32

18

14

0.808

27

19

8

0.763

Male

93

50

43

 

67

45

22

 

Age

<45

30

15

15

0.579

27

22

5

0.077

≥45

95

53

42

 

67

42

25

 

Tumor size (cm)

≤5

48

33

15

0.011

40

31

9

0.107

>5

77

35

42

 

54

33

21

 

AFP (ng/ml)

≤20

33

23

10

0.04

28

21

7

0.349

>20

92

45

47

 

66

43

23

 

HBsAg

Positive

110

61

49

0.521

57

39

18

0.622

Negative

15

7

8

 

37

25

12

 

Multiplicity

Single

82

49

33

0.097

59

40

19

0.938

Multiple (≥2)

43

19

24

 

35

24

11

 

Vascular invasion

Presence

67

28

39

0.002

52

29

23

0.004

Absence

58

40

18

 

42

35

7

 

Intrahepatic metastasis

Presence

59

21

38

<0.001

37

20

17

0.019

Absence

66

47

19

 

57

44

13

 

TNM stage

I/II

82

50

32

0.042

58

42

16

0.104

III/IV

43

18

25

 

36

22

14

 

Tumor Differentiation

poor

76

47

29

0.037

57

37

20

0.413

well

49

21

28

 

37

27

10

 
  1. P-values * were calculated using a chi-square (χ2) test. *P < 0.05.