Figure 8
From: Identification of pharmacological agents that induce HMGB1 release

Effects of SAHA, Azacitidine, Decitabine, Oxaliplatin, Fenbendazole and Oxibendazole on the acetylation of histones and HMGB1. U2OS cells were maintained in control conditions (Ctrl), or were treated with suberoylanilide hydroxamic acid (SAHA), azacitidine (AZA), decitabine (DECI), oxaliplatin (OXA), fenbendazole (FENB) and oxibendazole (OXIB) at the indicated concentrations for 6 (A) or 12 (B) h, followed by total protein extraction and detection of acetylated/deacetylated histones and HMGB1 by western blotting.