Figure 5

Hierarchical clustering of classified sequences at phylum (a) and order (b) classification level. The three experimental groups are indicated as SSc/GI+ (patients with established SSc and gastrointestinal symptoms), SSc/GI- (patients with SSc without gastrointestinal symptoms), and HC (healthy controls). Bars of different colors indicate he relative percentage of bacterial phyla (a) and orders (b) identified in each fecal sample. Only taxa participating with ≥5% in at least one sample are shown, while taxa with lower participations were added to the “other” sequence group. Similar samples were clustered using the average linkage algorithm.