Table 2 List of synthesized hexapeptides based on the computationally screened library.
From: Combating virulence of Gram-negative bacilli by OmpA inhibition
Name | Cyclic peptide | Purity (%) | Rational |
|---|---|---|---|
AOA-1 | &Arg-D-Pro-Trp-Arg-D-Pro-Trp& | 96 | Top-scoring docking peptide |
AOA-2 | &Trp-D-Pro-Arg-Trp-D-Pro-Arg& | 92 | Top-scoring docking peptide |
AOA-3 | &Arg-Pro-D-Trp-Arg-Pro-D-Trp& | 100 | Different stereoisomer |
AOA-4 | &D-Arg-Pro-Trp-D-Arg-Pro-Trp& | 95 | Different stereosiomer |
AOA-5 | &Ser-D-Pro-Trp-Ser-D-Pro-Trp& | 100 | Arg replaced by Ser |
AOA-6 | &Glu-D-Pro-Trp-Glu-D-Pro-Trp& | 95 | Arg replaced by Glu |
SXV4 | Ac-Trp-D-Pro-Arg-Trp-D-Pro-Arg-OH | 100 | Negative Control |
