Figure 3 | Scientific Reports

Figure 3

From: Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

Figure 3

Close-up of the chromosome 10 region displaying the strongest evidence of linkage. (a) Results from parametric linkage (HLOD) analysis under a dominant model, (b) LocusZoom plot (GRCh37 positions) of the -log base 10 of the HLOD equivalent p-value in the smaller (10 Mb ≈ 27 cM) region (shown within the red dashed lines on panel a) centred around the top SNP, rs7907300. Genes in this region are shown below the plot; the 4 omitted genes all lie to the left of GPR26 and thus outside the main region of significance.

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