Figure 2

Elevated gene expression of ssps, aaos and aad and increased in vitro AAO activity following exposure to aryl-alcohols and HMF. (A) Chemical structure of Veratryl alcohol (VA), 4-methoxybenzyl alcohol (MBA), benzyl alcohol (BA) and HMF (B) 30 mM of VA, 4- MBA, BA or HMF were added to P. ostreatus media. Relative gene expression to control of ssps (B), aad1 (C) and aao1,4, and 6 (D–F) was analyzed following 24 hours exposure to the chemicals. In vitro AAO activity in free cell extracts (G) was measured 24, 48 and 96 hours following the chemicals addition.